Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102536'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102536 (US8536175, 135) Show SMILES COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ncc(CN3CCOCC3)[nH]2)c2nccnc12 |(8.07,3.99,;8.85,2.66,;8.08,1.32,;8.85,-.01,;8.08,-1.34,;8.85,-2.68,;10.39,-2.68,;6.54,-1.34,;5.77,-2.68,;5.77,-.01,;6.54,1.32,;5.77,2.66,;4.23,-.01,;3.46,1.32,;1.92,1.32,;1.15,-.01,;-.39,-.01,;-1.16,1.32,;-1.16,-1.34,;-2.7,-1.34,;-3.61,-.1,;-5.07,-.57,;-5.07,-2.11,;-6.41,-2.88,;-7.74,-2.11,;-7.74,-.57,;-9.08,.2,;-10.41,-.57,;-10.41,-2.11,;-9.08,-2.88,;-3.61,-2.59,;1.92,-1.34,;1.15,-2.68,;1.92,-4.01,;3.46,-4.01,;4.23,-2.68,;3.46,-1.34,)| Show InChI InChI=1S/C25H24F2N6O4/c1-35-17-11-18(36-2)21(27)19(20(17)26)15-3-4-16(23-22(15)28-5-6-29-23)24(34)32-25-30-12-14(31-25)13-33-7-9-37-10-8-33/h3-6,11-12H,7-10,13H2,1-2H3,(H2,30,31,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
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