Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM128658'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM128658 (US8796244, 247) Show SMILES CC(C)Oc1cc(NC(=O)NCC(F)(F)F)cc(c1)-c1cnc2cc(ccn12)-c1nn2cc(C)nc2s1 Show InChI InChI=1S/C24H22F3N7O2S/c1-13(2)36-18-7-16(6-17(9-18)31-22(35)29-12-24(25,26)27)19-10-28-20-8-15(4-5-33(19)20)21-32-34-11-14(3)30-23(34)37-21/h4-11,13H,12H2,1-3H3,(H2,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.960	n/a	n/a	n/a	n/a	8.0	25
Astex Therapeutics Ltd US Patent					Assay Description Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...				US Patent US8796244 (2014) BindingDB Entry DOI: 10.7270/Q20C4TFP
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