Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM436197'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM436197 (US10590109, Compound 15 | US10590109, Compound 20) Show SMILES COCCNc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C23H28N8O4/c1-29-7-8-31(22(33)14-29)13-16-4-5-21(27-19(16)15-32)30(2)23(34)28-20-10-18(25-6-9-35-3)17(11-24)12-26-20/h4-5,10,12,15H,6-9,13-14H2,1-3H3,(H2,25,26,28,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM436197 (US10590109, Compound 15 | US10590109, Compound 20) Show SMILES COCCNc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C23H28N8O4/c1-29-7-8-31(22(33)14-29)13-16-4-5-21(27-19(16)15-32)30(2)23(34)28-20-10-18(25-6-9-35-3)17(11-24)12-26-20/h4-5,10,12,15H,6-9,13-14H2,1-3H3,(H2,25,26,28,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as reduction in cell viability incubated for 2 days by cell proliferation assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair