Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1 [1-336]' and Ligand = 'BDBM50157840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 [1-336] (Homo sapiens (Human))	BDBM50157840 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-...) Show SMILES On1c(=O)n(CC2COc3ccccc3O2)c2ccsc2c1=O Show InChI InChI=1S/C15H12N2O5S/c18-14-13-10(5-6-23-13)16(15(19)17(14)20)7-9-8-21-11-3-1-2-4-12(11)22-9/h1-6,9,20H,7-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	46.4	n/a	n/a	n/a	n/a	7.5	n/a
University of Sheffield					Assay Description Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...				Nat Chem Biol 12: 815-21 (2016) Article DOI: 10.1038/nchembio.2148 BindingDB Entry DOI: 10.7270/Q2RJ4H88
					More data for this Ligand-Target Pair				3D Structure (crystal)