Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 2 (Homo sapiens (Human)) | BDBM50450289 (CHEMBL4172928) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ogeda SA Curated by ChEMBL | Assay Description Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting method | Bioorg Med Chem 26: 5169-5180 (2018) Article DOI: 10.1016/j.bmc.2018.09.015 BindingDB Entry DOI: 10.7270/Q2RV0R8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 2 (Mus musculus) | BDBM50450289 (CHEMBL4172928) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Ogeda SA Curated by ChEMBL | Assay Description Agonist activity at mouse FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35... | Bioorg Med Chem 26: 5169-5180 (2018) Article DOI: 10.1016/j.bmc.2018.09.015 BindingDB Entry DOI: 10.7270/Q2RV0R8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 2 (Homo sapiens (Human)) | BDBM50450289 (CHEMBL4172928) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human FFAR2 expressed in HEK293 cells assessed as increase in cAMP level by HTRF assay | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127460 BindingDB Entry DOI: 10.7270/Q2HD807K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 2 (Homo sapiens (Human)) | BDBM50450289 (CHEMBL4172928) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Ogeda SA Curated by ChEMBL | Assay Description Agonist activity at human FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35... | Bioorg Med Chem 26: 5169-5180 (2018) Article DOI: 10.1016/j.bmc.2018.09.015 BindingDB Entry DOI: 10.7270/Q2RV0R8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 2 (Homo sapiens (Human)) | BDBM50450289 (CHEMBL4172928) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 209 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay | J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW | |||||||||||
More data for this Ligand-Target Pair |