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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50532034'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))		BDBM50532034
PNG
(CHEMBL4435859)
Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2ccccc2)n(n1)C1CCC(F)(F)CC1
Show InChI InChI=1S/C19H21F2N7O/c1-13-11-16(28(24-13)15-7-9-19(20,21)10-8-15)22-17(29)12-27-25-18(23-26-27)14-5-3-2-4-6-14/h2-6,11,15H,7-10,12H2,1H3,(H,22,29)
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Article
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n/an/an/an/a 383n/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay

Bioorg Med Chem Lett 29: 791-796 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.027
BindingDB Entry DOI: 10.7270/Q2BV7M47
More data for this
Ligand-Target Pair