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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 183' and Ligand = 'BDBM50011720'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 183


(Homo sapiens (Human))
BDBM50011720
PNG
(CHEMBL3262878)
Show SMILES Cc1ccc(OCC(=O)N2CCN(CC2)C(=O)Cc2ccccc2)cc1C
Show InChI InChI=1S/C22H26N2O3/c1-17-8-9-20(14-18(17)2)27-16-22(26)24-12-10-23(11-13-24)21(25)15-19-6-4-3-5-7-19/h3-9,14H,10-13,15-16H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.95E+3n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human EBI2 receptor expressed in CHO cells assessed as inhibition of NIBR51-induced intracellular calcium release ...


J Med Chem 57: 3358-68 (2014)


Article DOI: 10.1021/jm4019355
BindingDB Entry DOI: 10.7270/Q2BG2QJ5
More data for this
Ligand-Target Pair
G-protein coupled receptor 183


(Mus musculus)
BDBM50011720
PNG
(CHEMBL3262878)
Show SMILES Cc1ccc(OCC(=O)N2CCN(CC2)C(=O)Cc2ccccc2)cc1C
Show InChI InChI=1S/C22H26N2O3/c1-17-8-9-20(14-18(17)2)27-16-22(26)24-12-10-23(11-13-24)21(25)15-19-6-4-3-5-7-19/h3-9,14H,10-13,15-16H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.37E+3n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant mouse EBI2 receptor expressed in CHO cells assessed as inhibition of NIBR51-induced intracellular calcium release ...


J Med Chem 57: 3358-68 (2014)


Article DOI: 10.1021/jm4019355
BindingDB Entry DOI: 10.7270/Q2BG2QJ5
More data for this
Ligand-Target Pair