Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GTPase KRas (Homo sapiens (Human)) | BDBM50561645 (CHEMBL4760058) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to KRAS G12D mutant (unknown origin) using FAM-labelled peptide as substrate in absence of Tween20 by fluorescence polarization assa... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00022 BindingDB Entry DOI: 10.7270/Q26W9FSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase KRas (Homo sapiens (Human)) | BDBM50561645 (CHEMBL4760058) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to wild type KRAS (unknown origin) using FAM-labelled peptide as substrate in absence of Tween20 by fluorescence polarization assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00022 BindingDB Entry DOI: 10.7270/Q26W9FSJ | |||||||||||
More data for this Ligand-Target Pair |