Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM3363'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3363 (5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...) Show SMILES Cc1nc(CCCCCOC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C19H20ClN3O2/c1-14-16-11-12-17(20)22-23(16)18(21-14)10-6-3-7-13-25-19(24)15-8-4-2-5-9-15/h2,4-5,8-9,11-12H,3,6-7,10,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair