Found 16 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1' and Ligand = 'BDBM50026756' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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| PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla,
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 290: 989-97 (1999)
BindingDB Entry DOI: 10.7270/Q280515N |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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| PubMed
| 0.810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla,
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 290: 989-97 (1999)
BindingDB Entry DOI: 10.7270/Q280515N |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 39.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by PDSP Ki Database
| |
J Biol Chem 271: 27902-11 (1996)
Article DOI: 10.1074/jbc.271.44.27902 BindingDB Entry DOI: 10.7270/Q2FF3QV5 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 46.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by PDSP Ki Database
| |
J Biol Chem 271: 27902-11 (1996)
Article DOI: 10.1074/jbc.271.44.27902 BindingDB Entry DOI: 10.7270/Q2FF3QV5 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Clinic for Psychiatry
Curated by PDSP Ki Database
| |
Eur J Pharmacol 304: 155-62 (1996)
Article DOI: 10.1016/0014-2999(96)00088-x BindingDB Entry DOI: 10.7270/Q2HD7T6P |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 89.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
| |
Mol Pharmacol 49: 253-9 (1996)
BindingDB Entry DOI: 10.7270/Q2639N8C |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| Article PubMed
| 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universität Heidelberg
Curated by PDSP Ki Database
| |
Science 245: 1389-92 (1989)
Article DOI: 10.1126/science.2551039 BindingDB Entry DOI: 10.7270/Q2C53JCF |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by PDSP Ki Database
| |
J Biol Chem 271: 27902-11 (1996)
Article DOI: 10.1074/jbc.271.44.27902 BindingDB Entry DOI: 10.7270/Q2FF3QV5 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| PubMed
| 291 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
| |
Mol Pharmacol 43: 970-5 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2V1S |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 405 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universität Heidelberg
Curated by PDSP Ki Database
| |
Science 245: 1389-92 (1989)
Article DOI: 10.1126/science.2551039 BindingDB Entry DOI: 10.7270/Q2C53JCF |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 644 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Dental College
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 209-14 (1998)
Article DOI: 10.1016/s0006-2952(97)00433-4 BindingDB Entry DOI: 10.7270/Q2NP22ZJ |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by PDSP Ki Database
| |
Eur J Pharmacol 290: 37-47 (1995)
Article DOI: 10.1016/0922-4106(95)90014-4 BindingDB Entry DOI: 10.7270/Q2XK8D2R |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by PDSP Ki Database
| |
J Biol Chem 271: 27902-11 (1996)
Article DOI: 10.1074/jbc.271.44.27902 BindingDB Entry DOI: 10.7270/Q2FF3QV5 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Dental College
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 209-14 (1998)
Article DOI: 10.1016/s0006-2952(97)00433-4 BindingDB Entry DOI: 10.7270/Q2NP22ZJ |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Dental College
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 209-14 (1998)
Article DOI: 10.1016/s0006-2952(97)00433-4 BindingDB Entry DOI: 10.7270/Q2NP22ZJ |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat)) | BDBM50026756
(3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triaz...)Show InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Dental College
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 209-14 (1998)
Article DOI: 10.1016/s0006-2952(97)00433-4 BindingDB Entry DOI: 10.7270/Q2NP22ZJ |
More data for this Ligand-Target Pair | |