Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM403623'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM403623 ((1aS,2aR,6S,9S,10S,11R,23aR,23bS)-6-tert-butyl-N-[...) Show SMILES COc1ccc2nc(C=C)c(O[C@H]3CN([C@@H]([C@@H]3C)C(=O)OC(C)(C)C)C(=O)[C@@H](NC(=O)O[C@H]3C[C@H]4C[C@H]4[C@@H]3CCCC=C)C(C)(C)C)nc2c1 |r| Show InChI InChI=1S/C39H54N4O7/c1-11-13-14-15-25-26-18-23(26)19-30(25)49-37(46)42-33(38(4,5)6)35(44)43-21-31(22(3)32(43)36(45)50-39(7,8)9)48-34-27(12-2)40-28-17-16-24(47-10)20-29(28)41-34/h11-12,16-17,20,22-23,25-26,30-33H,1-2,13-15,18-19,21H2,3-10H3,(H,42,46)/t22-,23-,25+,26-,30+,31+,32+,33-/m1/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2930WJC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM403623 ((1aS,2aR,6S,9S,10S,11R,23aR,23bS)-6-tert-butyl-N-[...) Show SMILES COc1ccc2nc(C=C)c(O[C@H]3CN([C@@H]([C@@H]3C)C(=O)OC(C)(C)C)C(=O)[C@@H](NC(=O)O[C@H]3C[C@H]4C[C@H]4[C@@H]3CCCC=C)C(C)(C)C)nc2c1 |r| Show InChI InChI=1S/C39H54N4O7/c1-11-13-14-15-25-26-18-23(26)19-30(25)49-37(46)42-33(38(4,5)6)35(44)43-21-31(22(3)32(43)36(45)50-39(7,8)9)48-34-27(12-2)40-28-17-16-24(47-10)20-29(28)41-34/h11-12,16-17,20,22-23,25-26,30-33H,1-2,13-15,18-19,21H2,3-10H3,(H,42,46)/t22-,23-,25+,26-,30+,31+,32+,33-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2930WJC
					More data for this Ligand-Target Pair