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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079810'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Bos taurus (bovine))		BDBM50079810
PNG
(2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...)
Show SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1)C(O)=O
Show InChI InChI=1S/C25H39N3O4S2/c1-17(2)18(9-10-19(26)16-33)14-28-15-21(32-20-7-5-4-6-8-20)13-23(28)24(29)27-22(25(30)31)11-12-34-3/h4-10,17-19,21-23,33H,11-16,26H2,1-3H3,(H,27,29)(H,30,31)/b10-9+/t18-,19+,21-,22-,23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 150n/an/an/an/an/an/a



Eisai Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL protein

Bioorg Med Chem Lett 9: 2095-100 (1999)


BindingDB Entry DOI: 10.7270/Q2Z038PQ
More data for this
Ligand-Target Pair