BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ghrelin O-acyltransferase' and Ligand = 'BDBM396225'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin O-acyltransferase


(Homo sapiens (Human))		BDBM396225
PNG
(6-[5-Bromo-6-(3,3-difluoro-cyclobutylamino)-pyridi...)
Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NC2CC(F)(F)C2)n1
Show InChI InChI=1S/C16H15BrF2N6O/c1-7-10(12(20)13-15(21-7)25-26-24-13)4-8-2-3-11(17)14(22-8)23-9-5-16(18,19)6-9/h2-3,9H,4-6,20H2,1H3,(H,22,23)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0960n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...

Bioorg Med Chem Lett 17: 4664-9 (2007)


BindingDB Entry DOI: 10.7270/Q2VH5R5S
More data for this
Ligand-Target Pair