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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM18746'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18746
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-[1-(pr...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(C(C)OCC=C)c2c1 |t:18|
Show InChI InChI=1S/C23H26FNO2/c1-6-11-27-15(2)20-14-23(3,4)25-21-9-7-16(12-19(20)21)18-13-17(24)8-10-22(18)26-5/h6-10,12-15,25H,1,11H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 34n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair