BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50113780'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50113780 ((2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptor				J Med Chem 45: 2417-24 (2002) BindingDB Entry DOI: 10.7270/Q2HT2Q1F
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50113780 ((2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]DEX from human glucocorticoid receptor				J Med Chem 53: 3065-74 (2010) Article DOI: 10.1021/jm901452y BindingDB Entry DOI: 10.7270/Q2VQ33NH
Trinity College Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50113780 ((2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
Corcept Therapeutics Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50113780 ((2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor in SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression by MMTV5 r...				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
Corcept Therapeutics Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50113780 ((2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Binding affinity to glucocorticoid receptor in SW1353 cells by whole-cell binding assay				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
Corcept Therapeutics Curated by ChEMBL					More data for this Ligand-Target Pair