BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50203584'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50203584
PNG
((8S,11R,13S,14S,17S)-11-(4-(diphenylphosphoryl)phe...)
Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)c1ccccc1)c1ccc(cc1)P(=O)(c1ccccc1)c1ccccc1 |c:4,10|
Show InChI InChI=1S/C42H41O3P/c1-41-28-38(29-17-21-35(22-18-29)46(45,33-13-7-3-8-14-33)34-15-9-4-10-16-34)40-36-24-20-32(43)27-30(36)19-23-37(40)39(41)25-26-42(41,44)31-11-5-2-6-12-31/h2-18,21-22,27,37-39,44H,19-20,23-26,28H2,1H3/t37-,38+,39-,41-,42+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 20n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development L.L.C.

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...

Bioorg Med Chem Lett 17: 1471-4 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.003
BindingDB Entry DOI: 10.7270/Q2PN96GJ
More data for this
Ligand-Target Pair