Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50249142'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249142 (CHEMBL514455 | N-(4,5-dimethyl-1,3-thiazol-2-yl)-1...) Show SMILES Cc1nc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc32)sc1C |TLB:8:7:11.16:18.23,15:16:9.7:18.23,19:18:11.16:9.7,THB:5:7:11.16:18.23,(38.26,-10.94,;36.85,-11.59,;36.55,-13.1,;35.01,-13.28,;34.26,-14.62,;32.71,-14.64,;31.93,-13.31,;31.96,-15.98,;30.62,-15.21,;32.47,-16.75,;32.47,-18.94,;30.61,-19.46,;29.26,-20.23,;27.93,-19.46,;27.93,-17.91,;29.26,-17.14,;30.57,-18.06,;31.96,-17.4,;33.49,-18.29,;34.76,-17.55,;36.04,-18.28,;36.05,-19.77,;34.77,-20.51,;33.49,-19.77,;34.38,-11.88,;35.51,-10.83,;35.33,-9.3,)| Show InChI InChI=1S/C23H22N2OS/c1-13-14(2)27-22(24-13)25-21(26)23(3)12-19-15-8-4-6-10-17(15)20(23)18-11-7-5-9-16(18)19/h4-11,19-20H,12H2,1-3H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assay				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50249142 (CHEMBL514455 | N-(4,5-dimethyl-1,3-thiazol-2-yl)-1...) Show SMILES Cc1nc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc32)sc1C |TLB:8:7:11.16:18.23,15:16:9.7:18.23,19:18:11.16:9.7,THB:5:7:11.16:18.23,(38.26,-10.94,;36.85,-11.59,;36.55,-13.1,;35.01,-13.28,;34.26,-14.62,;32.71,-14.64,;31.93,-13.31,;31.96,-15.98,;30.62,-15.21,;32.47,-16.75,;32.47,-18.94,;30.61,-19.46,;29.26,-20.23,;27.93,-19.46,;27.93,-17.91,;29.26,-17.14,;30.57,-18.06,;31.96,-17.4,;33.49,-18.29,;34.76,-17.55,;36.04,-18.28,;36.05,-19.77,;34.77,-20.51,;33.49,-19.77,;34.38,-11.88,;35.51,-10.83,;35.33,-9.3,)| Show InChI InChI=1S/C23H22N2OS/c1-13-14(2)27-22(24-13)25-21(26)23(3)12-19-15-8-4-6-10-17(15)20(23)18-11-7-5-9-16(18)19/h4-11,19-20H,12H2,1-3H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	923	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...				Bioorg Med Chem Lett 19: 2139-43 (2009) Article DOI: 10.1016/j.bmcl.2009.03.006 BindingDB Entry DOI: 10.7270/Q2XW4KRC
					More data for this Ligand-Target Pair