Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50316561'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human MDA-kb2 cells transfected with MMTV-LUC assessed as induction of MMTV-LTR/promoter linked LUC ge...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair