Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50334051'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter ...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair