Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM521616'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM521616 (US11149054, Compound 4585) Show SMILES CO[C@H]1CC[C@](O)(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC[C@H]5C[C@@](O)(CC[C@]5(C)[C@H]4CC[C@]23C)C(F)(F)F)CC1 |r,wU:18.18,26.28,14.13,20.20,24.25,11.10,5.6,29.33,wD:15.15,20.34,9.9,5.5,2.1,(9.47,-.28,;7.99,-.68,;6.9,.41,;7.3,1.9,;6.21,2.99,;4.72,2.59,;4.72,4.13,;3.21,2.27,;2.18,3.41,;.68,3.09,;-.35,4.24,;.2,1.63,;1.11,.38,;.2,-.86,;-1.26,-.39,;-2.6,-1.16,;-2.6,-2.7,;-3.93,-3.47,;-5.27,-2.7,;-6.6,-3.47,;-7.93,-2.7,;-9.02,-3.79,;-7.93,-1.16,;-6.6,-.39,;-5.27,-1.16,;-5.27,.38,;-3.93,-.39,;-3.93,1.15,;-2.6,1.92,;-1.26,1.15,;-1.1,2.68,;-9.47,-2.7,;-10.24,-1.36,;-10.24,-4.03,;-11.01,-2.7,;4.32,1.1,;5.41,.01,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	166	n/a	n/a	n/a	n/a
TBA					Assay Description The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...				Citation and Details BindingDB Entry DOI: 10.7270/Q24X5BZR
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