Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50200526 (CHEMBL1234118) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]kainate from human GluK1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method | J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |