Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-AMPA as radioliga... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-kainate as radiol... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-kainate as radiol... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cells | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Agonist activity at GluK2 (unknown origin) | J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Effective concentration against human GluR6 expressed in HEK293 cells | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair |