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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminase liver isoform, mitochondrial' and Ligand = 'BDBM50238210'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutaminase liver isoform, mitochondrial


(Homo sapiens)		BDBM50238210
PNG
(CHEMBL4065595)
Show SMILES CCc1cc(ccc1\C=C1/SC(=O)NC1=O)-c1ccc(cc1C#N)-n1c(C)cc(\C=C2/SC(=O)NC2=O)c1C
Show InChI InChI=1S/C29H22N4O4S2/c1-4-17-10-19(6-5-18(17)12-24-26(34)31-28(36)38-24)23-8-7-22(11-21(23)14-30)33-15(2)9-20(16(33)3)13-25-27(35)32-29(37)39-25/h5-13H,4H2,1-3H3,(H,31,34,36)(H,32,35,37)/b24-12-,25-13-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preinc...

J Med Chem 60: 5599-5612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00282
BindingDB Entry DOI: 10.7270/Q26H4KP5
More data for this
Ligand-Target Pair