Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM50153546'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50153546 (3-(2,6-Dichloro-phenyl)-5-[2-(2-oxo-pyrrolidin-1-y...) Show SMILES CCN(CC)c1ccc(NC(=O)c2c(CCN3CCCC3=O)onc2-c2c(Cl)cccc2Cl)cc1 |(8.03,-3.46,;6.56,-2.99,;6.23,-1.5,;7.38,-.45,;8.85,-.92,;4.77,-1.01,;3.62,-2.06,;2.18,-1.57,;1.85,-.08,;.38,.39,;-.75,-.64,;-.44,-2.13,;-2.23,-.17,;-2.7,1.3,;-1.81,2.54,;-2.43,3.96,;-1.53,5.19,;,5.19,;.47,6.66,;-.79,7.54,;-2.02,6.66,;-3.49,7.13,;-4.24,1.3,;-4.73,-.17,;-3.47,-1.06,;-3.47,-2.6,;-4.8,-3.39,;-6.13,-2.6,;-4.8,-4.92,;-3.47,-5.7,;-2.11,-4.92,;-2.11,-3.37,;-.58,-3.37,;2.99,.95,;4.44,.49,)| Show InChI InChI=1S/C26H28Cl2N4O3/c1-3-31(4-2)18-12-10-17(11-13-18)29-26(34)24-21(14-16-32-15-6-9-22(32)33)35-30-25(24)23-19(27)7-5-8-20(23)28/h5,7-8,10-13H,3-4,6,9,14-16H2,1-2H3,(H,29,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assay				Bioorg Med Chem Lett 14: 5223-6 (2004) Article DOI: 10.1016/j.bmcl.2004.06.060 BindingDB Entry DOI: 10.7270/Q2Z60NJD
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50153546 (3-(2,6-Dichloro-phenyl)-5-[2-(2-oxo-pyrrolidin-1-y...) Show SMILES CCN(CC)c1ccc(NC(=O)c2c(CCN3CCCC3=O)onc2-c2c(Cl)cccc2Cl)cc1 |(8.03,-3.46,;6.56,-2.99,;6.23,-1.5,;7.38,-.45,;8.85,-.92,;4.77,-1.01,;3.62,-2.06,;2.18,-1.57,;1.85,-.08,;.38,.39,;-.75,-.64,;-.44,-2.13,;-2.23,-.17,;-2.7,1.3,;-1.81,2.54,;-2.43,3.96,;-1.53,5.19,;,5.19,;.47,6.66,;-.79,7.54,;-2.02,6.66,;-3.49,7.13,;-4.24,1.3,;-4.73,-.17,;-3.47,-1.06,;-3.47,-2.6,;-4.8,-3.39,;-6.13,-2.6,;-4.8,-4.92,;-3.47,-5.7,;-2.11,-4.92,;-2.11,-3.37,;-.58,-3.37,;2.99,.95,;4.44,.49,)| Show InChI InChI=1S/C26H28Cl2N4O3/c1-3-31(4-2)18-12-10-17(11-13-18)29-26(34)24-21(14-16-32-15-6-9-22(32)33)35-30-25(24)23-19(27)7-5-8-20(23)28/h5,7-8,10-13H,3-4,6,9,14-16H2,1-2H3,(H,29,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to displace [125I]-ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)				Bioorg Med Chem Lett 14: 5223-6 (2004) Article DOI: 10.1016/j.bmcl.2004.06.060 BindingDB Entry DOI: 10.7270/Q2Z60NJD
					More data for this Ligand-Target Pair