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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HTH-type transcriptional regulator ExsA' and Ligand = 'BDBM50378357'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTH-type transcriptional regulator ExsA


(Pseudomonas aeruginosa)		BDBM50378357
PNG
(CHEMBL575329)
Show SMILES On1c(nc2ccc(cc12)[N+]([O-])=O)-c1ccc(NC(=O)\C=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C22H15FN4O4/c23-16-6-1-14(2-7-16)3-12-21(28)24-17-8-4-15(5-9-17)22-25-19-11-10-18(27(30)31)13-20(19)26(22)29/h1-13,29H,(H,24,28)/b12-3+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Paratek Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa ExsA binding to DNA

J Med Chem 52: 5626-34 (2009)


Article DOI: 10.1021/jm9006577
BindingDB Entry DOI: 10.7270/Q2XD12KZ
More data for this
Ligand-Target Pair