Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50248056'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248056 ((S)-N-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbon...) Show SMILES CN(C)[C@H]1CCN(C1)C(=O)c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2s1 |r| Show InChI InChI=1S/C30H29FN6O4S/c1-34(2)21-11-13-35(18-21)28(38)26-17-23-27(42-26)25(10-12-32-23)41-24-9-8-19(16-22(24)31)33-29(39)37-15-14-36(30(37)40)20-6-4-3-5-7-20/h3-10,12,16-17,21H,11,13-15,18H2,1-2H3,(H,33,39)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant c-Met (unknown origin) catalytic domain expressed in baculovirus-infected Trichoplusia ni Hi5 cells after 30 mins...				Bioorg Med Chem Lett 19: 1323-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.068 BindingDB Entry DOI: 10.7270/Q23F4PHJ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248056 ((S)-N-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbon...) Show SMILES CN(C)[C@H]1CCN(C1)C(=O)c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2s1 |r| Show InChI InChI=1S/C30H29FN6O4S/c1-34(2)21-11-13-35(18-21)28(38)26-17-23-27(42-26)25(10-12-32-23)41-24-9-8-19(16-22(24)31)33-29(39)37-15-14-36(30(37)40)20-6-4-3-5-7-20/h3-10,12,16-17,21H,11,13-15,18H2,1-2H3,(H,33,39)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50248056 ((S)-N-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbon...) Show SMILES CN(C)[C@H]1CCN(C1)C(=O)c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2s1 |r| Show InChI InChI=1S/C30H29FN6O4S/c1-34(2)21-11-13-35(18-21)28(38)26-17-23-27(42-26)25(10-12-32-23)41-24-9-8-19(16-22(24)31)33-29(39)37-15-14-36(30(37)40)20-6-4-3-5-7-20/h3-10,12,16-17,21H,11,13-15,18H2,1-2H3,(H,33,39)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of TPR-fused Met (unknown origin) phosphorylation expressed in human 293T cells by ELISA				Bioorg Med Chem Lett 19: 1323-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.068 BindingDB Entry DOI: 10.7270/Q23F4PHJ
					More data for this Ligand-Target Pair