Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50440890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440890 (CHEMBL2431841 | US9066954, 341) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	9.10	-46.2	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440890 (CHEMBL2431841 | US9066954, 341) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal His-6-tagged human recombinant c-Met (974 to 1390) using Ac-ARDMYDKEYYSVHNK as substrate by spectrophotometric assay				J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440890 (CHEMBL2431841 | US9066954, 341) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met autophosphorylation in human A549 cells after 1 hr by ELISA				J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440890 (CHEMBL2431841 | US9066954, 341) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Hutchison MediPharma Limited Curated by ChEMBL					Assay Description Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA				J Med Chem 57: 7577-89 (2014) Article DOI: 10.1021/jm500510f BindingDB Entry DOI: 10.7270/Q2JD4ZCR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440890 (CHEMBL2431841 | US9066954, 341) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Hutchison MediPharma Limited Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay				J Med Chem 57: 7577-89 (2014) Article DOI: 10.1021/jm500510f BindingDB Entry DOI: 10.7270/Q2JD4ZCR
					More data for this Ligand-Target Pair