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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM50248329'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hexokinase-4


(Homo sapiens (Human))
BDBM50248329
PNG
(2-amino-5-(2-methoxyphenoxy)-N-(4-methylthiazol-2-...)
Show SMILES COc1ccccc1Oc1ccc(N)c(c1)C(=O)Nc1nc(C)cs1
Show InChI InChI=1S/C18H17N3O3S/c1-11-10-25-18(20-11)21-17(22)13-9-12(7-8-14(13)19)24-16-6-4-3-5-15(16)23-2/h3-10H,19H2,1-2H3,(H,20,21,22)
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Article
PubMed
n/an/an/an/a 120n/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucose


Bioorg Med Chem Lett 19: 1357-60 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.053
BindingDB Entry DOI: 10.7270/Q2PC3285
More data for this
Ligand-Target Pair
Hexokinase-4


(Homo sapiens (Human))
BDBM50248329
PNG
(2-amino-5-(2-methoxyphenoxy)-N-(4-methylthiazol-2-...)
Show SMILES COc1ccccc1Oc1ccc(N)c(c1)C(=O)Nc1nc(C)cs1
Show InChI InChI=1S/C18H17N3O3S/c1-11-10-25-18(20-11)21-17(22)13-9-12(7-8-14(13)19)24-16-6-4-3-5-15(16)23-2/h3-10H,19H2,1-2H3,(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 410n/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucose


Bioorg Med Chem Lett 19: 1357-60 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.053
BindingDB Entry DOI: 10.7270/Q2PC3285
More data for this
Ligand-Target Pair