Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM426311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM426311 (US10513524, Compound (P1)) Show SMILES Fc1ccc(cc1)-c1ncc2n1nc(CN1CC(C1)Oc1ccncc1)[nH]c2=O Show InChI InChI=1S/C20H17FN6O2/c21-14-3-1-13(2-4-14)19-23-9-17-20(28)24-18(25-27(17)19)12-26-10-16(11-26)29-15-5-7-22-8-6-15/h1-9,16H,10-12H2,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
H. LUNDBECK A/S US Patent					Assay Description A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...				US Patent US10513524 (2019) BindingDB Entry DOI: 10.7270/Q2G44SNW
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