Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM127672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM127672 (US8791123, 45) Show SMILES NS(=O)(=O)N1CCC(CC1)NC(=O)c1cnn2ccc(nc12)N1CCCC1c1cc(F)ccc1F Show InChI InChI=1S/C22H25F2N7O3S/c23-14-3-4-18(24)16(12-14)19-2-1-8-30(19)20-7-11-31-21(28-20)17(13-26-31)22(32)27-15-5-9-29(10-6-15)35(25,33)34/h3-4,7,11-13,15,19H,1-2,5-6,8-10H2,(H,27,32)(H2,25,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	n/a
Array Biopharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US8791123 (2014) BindingDB Entry DOI: 10.7270/Q2Q23XX7
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