Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM127682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM127682 (US8791123, 55 | US8791123, 56) Show SMILES OCC(O)CNC(=O)c1cnn2ccc(nc12)N1CCCC1c1cc(F)ccc1CO Show InChI InChI=1S/C21H24FN5O4/c22-14-4-3-13(11-28)16(8-14)18-2-1-6-26(18)19-5-7-27-20(25-19)17(10-24-27)21(31)23-9-15(30)12-29/h3-5,7-8,10,15,18,28-30H,1-2,6,9,11-12H2,(H,23,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Array Biopharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US8791123 (2014) BindingDB Entry DOI: 10.7270/Q2Q23XX7
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM127682 (US8791123, 55 | US8791123, 56) Show SMILES OCC(O)CNC(=O)c1cnn2ccc(nc12)N1CCCC1c1cc(F)ccc1CO Show InChI InChI=1S/C21H24FN5O4/c22-14-4-3-13(11-28)16(8-14)18-2-1-6-26(18)19-5-7-27-20(25-19)17(10-24-27)21(31)23-9-15(30)12-29/h3-5,7-8,10,15,18,28-30H,1-2,6,9,11-12H2,(H,23,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.5	n/a
Array Biopharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US8791123 (2014) BindingDB Entry DOI: 10.7270/Q2Q23XX7
					More data for this Ligand-Target Pair