Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM24915 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Pfizer | Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar... | Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5 | |||||||||||
More data for this Ligand-Target Pair |