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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50002120'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50002120
PNG
(2-(3-Chloro-phenyl)-3-(3-dimethylamino-propyl)-thi...)
Show SMILES CN(C)CCCN1C(SCC1=O)c1cccc(Cl)c1
Show InChI InChI=1S/C14H19ClN2OS/c1-16(2)7-4-8-17-13(18)10-19-14(17)11-5-3-6-12(15)9-11/h3,5-6,9,14H,4,7-8,10H2,1-2H3
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CHEMBL
PC cid
PC sid
UniChem

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PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Universit£ di Napoli Federico II

Curated by ChEMBL


Assay Description
In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileum

J Med Chem 35: 2910-2 (1992)


BindingDB Entry DOI: 10.7270/Q2XK8G4G
More data for this
Ligand-Target Pair