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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50159114'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50159114
PNG
(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Show SMILES O=C(C1CC1)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1
Show InChI InChI=1S/C20H23N3O/c24-20(14-1-2-14)16-3-7-18-15(13-16)4-8-19(21-18)23-11-9-22(10-12-23)17-5-6-17/h3-4,7-8,13-14,17H,1-2,5-6,9-12H2
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PC sid
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]-pyrilamine binding to human H1 histamine receptor


J Med Chem 48: 306-11 (2005)


Article DOI: 10.1021/jm040873u
BindingDB Entry DOI: 10.7270/Q2N0161T
More data for this
Ligand-Target Pair