Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50070213'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50070213 (3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]...) Show SMILES Clc1ccc(Cc2noc(CCc3cnc[nH]3)n2)cc1 Show InChI InChI=1S/C14H13ClN4O/c15-11-3-1-10(2-4-11)7-13-18-14(20-19-13)6-5-12-8-16-9-17-12/h1-4,8-9H,5-7H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from histamine H3 receptor in rat brain membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50070213 (3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]...) Show SMILES Clc1ccc(Cc2noc(CCc3cnc[nH]3)n2)cc1 Show InChI InChI=1S/C14H13ClN4O/c15-11-3-1-10(2-4-11)7-13-18-14(20-19-13)6-5-12-8-16-9-17-12/h1-4,8-9H,5-7H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against H3 receptor in rat cerebral cortex membranes was evaluated using [3H]N-methyl-histamine as radioligand				Citation and Details BindingDB Entry DOI: 10.7270/Q2GF0WP5
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50070213 (3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]...) Show SMILES Clc1ccc(Cc2noc(CCc3cnc[nH]3)n2)cc1 Show InChI InChI=1S/C14H13ClN4O/c15-11-3-1-10(2-4-11)7-13-18-14(20-19-13)6-5-12-8-16-9-17-12/h1-4,8-9H,5-7H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gliatech Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-alpha-methylhistamine from histamine H3 receptor				Bioorg Med Chem Lett 8: 1133-8 (1999) BindingDB Entry DOI: 10.7270/Q2GF0SPX
					More data for this Ligand-Target Pair