| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50070213 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1776531 (CHEMBL4233523) |
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| Ki | 2.5±n/a nM |
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| Citation |  Khanfar, MA; Reiner, D; Hagenow, S; Stark, H Design, synthesis, and biological evaluation of novel oxadiazole- and thiazole-based histamine H Bioorg Med Chem26:4034-4046 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50070213 |
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| n/a |
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| Name | BDBM50070213 |
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| Synonyms: | 3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]-[1,2,4]oxadiazole | CHEMBL276798 | GR-175737 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13ClN4O |
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| Mol. Mass. | 288.732 |
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| SMILES | Clc1ccc(Cc2noc(CCc3cnc[nH]3)n2)cc1 |
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| Structure | 
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