Compile Data Set for Download or QSAR

Found 407 hits with Last Name = 'hagenow' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580518 (CHEMBL5089580) Show SMILES Nc1nc2-c3ccccc3C(=O)c2c(n1)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Inhibition of human H3 receptor				Eur J Med Chem 152: 223-234 (2018) Article DOI: 10.1016/j.ejmech.2018.04.043 BindingDB Entry DOI: 10.7270/Q2697632
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580523 (CHEMBL5093850) Show SMILES Nc1nc2-c3ccc(OCCCN4CCCCC4)cc3C(=O)c2c(n1)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580512 (CHEMBL5072724) Show SMILES Nc1nc-2c(Cc3ccccc-23)c(n1)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580514 (CHEMBL5093935) Show SMILES Nc1nc-2c(Cc3cc(OCCCN4CCCCC4)ccc-23)c(n1)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50202986 (2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]...) Show SMILES COCCOc1ccc(cc1)N1CCN(CCn2ncc3c2nc(N)n2nc(nc32)-c2ccco2)CC1 Show InChI InChI=1S/C25H29N9O3/c1-35-15-16-36-19-6-4-18(5-7-19)32-11-8-31(9-12-32)10-13-33-23-20(17-27-33)24-28-22(21-3-2-14-37-21)30-34(24)25(26)29-23/h2-7,14,17H,8-13,15-16H2,1H3,(H2,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458224 (CHEMBL2297871) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H25NO2/c20-18(15-5-6-15)16-7-9-17(10-8-16)21-14-4-13-19-11-2-1-3-12-19/h7-10,15H,1-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human H3R expressed in CHOK1 cell membranes after 60 mins by gamma counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458219 (CHEMBL4209497) Show SMILES O=C1\C(Cc2ccccc12)=C\c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C24H27NO2/c26-24-21(18-20-7-2-3-8-23(20)24)17-19-9-11-22(12-10-19)27-16-6-15-25-13-4-1-5-14-25/h2-3,7-12,17H,1,4-6,13-16,18H2/b21-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-(R)alpha-MeHA from rat brain H3 receptor				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458228 (CHEMBL4218833) Show SMILES Fc1ccc2C(=O)\C(Cc2c1)=C\c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C24H26FNO2/c25-21-7-10-23-19(17-21)16-20(24(23)27)15-18-5-8-22(9-6-18)28-14-4-13-26-11-2-1-3-12-26/h5-10,15,17H,1-4,11-14,16H2/b20-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580516 (CHEMBL5094415) Show SMILES Nc1nc-2c(Cc3cc(OCCCN4CCCCC4)ccc-23)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50070213 (3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]...) Show SMILES Clc1ccc(Cc2noc(CCc3cnc[nH]3)n2)cc1 Show InChI InChI=1S/C14H13ClN4O/c15-11-3-1-10(2-4-11)7-13-18-14(20-19-13)6-5-12-8-16-9-17-12/h1-4,8-9H,5-7H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from histamine H3 receptor in rat brain membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50462785 (CHEMBL4245973) Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)-c1nc(C)c(s1)C(=O)N1CCOCC1 |r| Show InChI InChI=1S/C23H31N3O3S/c1-17-5-3-10-25(17)11-4-14-29-20-8-6-19(7-9-20)22-24-18(2)21(30-22)23(27)26-12-15-28-16-13-26/h6-9,17H,3-5,10-16H2,1-2H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cell membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50525644 (CHEMBL4545912) Show SMILES C#CCNC1CCc2cc(OCCCN3CCCCC3)ccc12 Show InChI InChI=1S/C20H28N2O/c1-2-11-21-20-10-7-17-16-18(8-9-19(17)20)23-15-6-14-22-12-4-3-5-13-22/h1,8-9,16,20-21H,3-7,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant H3 receptor expressed in HEK293 cells incubated for 90 min				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.016 BindingDB Entry DOI: 10.7270/Q24B34RZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from human striatal full length H3 receptor after 60 mins by gamma counting method				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50413824 (CHEMBL473093) Show SMILES CCCN1CCN(CC1)c1ncc(CCN(C)CCCc2ccccc2)s1 Show InChI InChI=1S/C22H34N4S/c1-3-12-25-15-17-26(18-16-25)22-23-19-21(27-22)11-14-24(2)13-7-10-20-8-5-4-6-9-20/h4-6,8-9,19H,3,7,10-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293T cell membranes after 60 mins by liquid scintillatio...				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458234 (CHEMBL4212330) Show SMILES O=C1\C(Cc2cc(OCCCN3CCCCC3)ccc12)=C\c1ccccc1 Show InChI InChI=1S/C24H27NO2/c26-24-21(16-19-8-3-1-4-9-19)17-20-18-22(10-11-23(20)24)27-15-7-14-25-12-5-2-6-13-25/h1,3-4,8-11,16,18H,2,5-7,12-15,17H2/b21-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50580522 (CHEMBL5082650) Show SMILES Nc1nc2-c3cc(OCCCN4CCCCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50462811 (CHEMBL4240664) Show SMILES Cc1sc(nc1OCCN1CCCC1)-c1ccc(cc1)C#N Show InChI InChI=1S/C17H19N3OS/c1-13-16(21-11-10-20-8-2-3-9-20)19-17(22-13)15-6-4-14(12-18)5-7-15/h4-7H,2-3,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580517 (CHEMBL5084903) Show SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCCC4)cc-23)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50580517 (CHEMBL5084903) Show SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCCC4)cc-23)c(n1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50520939 (CHEMBL4449790) Show SMILES CCC(=O)c1ccc(OCCCN2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C21H27N3O2/c1-2-21(25)18-4-6-20(7-5-18)26-17-3-12-23-13-15-24(16-14-23)19-8-10-22-11-9-19/h4-11H,2-3,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from full length recombinant human H3R expressed in HEK293 cell membranes after 90 mins by beta scintilla...				Bioorg Med Chem 26: 6056-6066 (2018) Article DOI: 10.1016/j.bmc.2018.11.010 BindingDB Entry DOI: 10.7270/Q2NV9NNX
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50462808 (CHEMBL4240159) Show SMILES Cc1sc(nc1OC(=O)N1CCC(CC1)N1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C21H27N3O2S/c1-16-19(22-20(27-16)17-8-4-2-5-9-17)26-21(25)24-14-10-18(11-15-24)23-12-6-3-7-13-23/h2,4-5,8-9,18H,3,6-7,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50272040 (CHEMBL4129950) Show SMILES C[C@@H](NCc1ccc(OCc2ccc(OCCCN3CCCCC3)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C25H35N3O3/c1-20(25(26)29)27-18-21-6-10-24(11-7-21)31-19-22-8-12-23(13-9-22)30-17-5-16-28-14-3-2-4-15-28/h6-13,20,27H,2-5,14-19H2,1H3,(H2,26,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]-Nalpha-MeHA from human H3 receptor expressed in HEK293 cell membranes by scintillation counting method				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50580520 (CHEMBL5082920) Show SMILES Nc1nc2-c3cc(OCCCN4CCCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from human striatal full length H3 receptor expressed in CHOK1 cells after 60 mins				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458227 (CHEMBL4205653) Show SMILES Brc1ccc(COc2ccc3C(=O)\C(Cc3c2)=C\c2ccc(OCCCN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C31H32BrNO3/c32-27-9-5-24(6-10-27)22-36-29-13-14-30-25(21-29)20-26(31(30)34)19-23-7-11-28(12-8-23)35-18-4-17-33-15-2-1-3-16-33/h5-14,19,21H,1-4,15-18,20,22H2/b26-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50525645 (CHEMBL4553116) Show SMILES C#CCNC1CCc2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C20H28N2O/c1-2-11-21-20-10-8-17-7-9-18(16-19(17)20)23-15-6-14-22-12-4-3-5-13-22/h1,7,9,16,20-21H,3-6,8,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant H3 receptor expressed in HEK293 cells incubated for 90 min				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.016 BindingDB Entry DOI: 10.7270/Q24B34RZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50462821 (CHEMBL4247219) Show SMILES Cc1sc(nc1OCc1ccc(CN2CCCCC2)cc1)-c1cnccn1 Show InChI InChI=1S/C21H24N4OS/c1-16-20(24-21(27-16)19-13-22-9-10-23-19)26-15-18-7-5-17(6-8-18)14-25-11-3-2-4-12-25/h5-10,13H,2-4,11-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membranes				Bioorg Med Chem 26: 4034-4046 (2018) Article DOI: 10.1016/j.bmc.2018.06.028 BindingDB Entry DOI: 10.7270/Q29026FG
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50580515 (CHEMBL5088622) Show SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCC4)cc-23)c(n1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50316887 (2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[...) Show SMILES Nc1nc2-c3cc(OCCN4CCOCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI InChI=1S/C23H22N4O3/c24-23-25-20(15-4-2-1-3-5-15)19-21(26-23)18-14-16(6-7-17(18)22(19)28)30-13-10-27-8-11-29-12-9-27/h1-7,14H,8-13H2,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50405715 (CHEMBL4173079) Show SMILES CCC(C)(C)c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C19H21NO3S2/c1-12(11-24)18(21)20-10-16(9-17(20)19(22)23)25-15-7-6-13-4-2-3-5-14(13)8-15/h2-8,12,16-17,24H,9-11H2,1H3,(H,22,23)/t12-,16+,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from recombinant human H3 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countin...				Eur J Med Chem 152: 223-234 (2018) Article DOI: 10.1016/j.ejmech.2018.04.043 BindingDB Entry DOI: 10.7270/Q2697632
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50525645 (CHEMBL4553116) Show SMILES C#CCNC1CCc2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C20H28N2O/c1-2-11-21-20-10-8-17-7-9-18(16-19(17)20)23-15-6-14-22-12-4-3-5-13-22/h1,7,9,16,20-21H,3-6,8,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant H3 receptor expressed in HEK293 cells incubated for 90 min				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.016 BindingDB Entry DOI: 10.7270/Q24B34RZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50525644 (CHEMBL4545912) Show SMILES C#CCNC1CCc2cc(OCCCN3CCCCC3)ccc12 Show InChI InChI=1S/C20H28N2O/c1-2-11-21-20-10-7-17-16-18(8-9-19(17)20)23-15-6-14-22-12-4-3-5-13-22/h1,8-9,16,20-21H,3-7,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant H3 receptor expressed in HEK293 cells incubated for 90 min				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.08.016 BindingDB Entry DOI: 10.7270/Q24B34RZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50520922 (CHEMBL4547780) Show SMILES CC(=O)c1ccc(OCCCN2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C20H25N3O2/c1-17(24)18-3-5-20(6-4-18)25-16-2-11-22-12-14-23(15-13-22)19-7-9-21-10-8-19/h3-10H,2,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from full length recombinant human H3R expressed in HEK293 cell membranes after 90 mins by beta scintilla...				Bioorg Med Chem 26: 6056-6066 (2018) Article DOI: 10.1016/j.bmc.2018.11.010 BindingDB Entry DOI: 10.7270/Q2NV9NNX
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50580522 (CHEMBL5082650) Show SMILES Nc1nc2-c3cc(OCCCN4CCCCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580513 (CHEMBL5094263) Show SMILES Nc1nc-2c(Cc3cc(OCCCN4CCCC4)ccc-23)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580515 (CHEMBL5088622) Show SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCC4)cc-23)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458224 (CHEMBL2297871) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H25NO2/c20-18(15-5-6-15)16-7-9-17(10-8-16)21-14-4-13-19-11-2-1-3-12-19/h7-10,15H,1-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50172447 ((E)-N-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinoli...) Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC)cc3)ccc2n1 Show InChI InChI=1S/C26H30N4O2/c1-4-29-13-15-30(16-14-29)25-17-19(2)23-18-21(8-11-24(23)28-25)27-26(31)12-7-20-5-9-22(32-3)10-6-20/h5-12,17-18H,4,13-16H2,1-3H3,(H,27,31)/b12-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical and Medicinal Chemistry, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analysi...				ACS Med Chem Lett 8: 648-653 (2017) Article DOI: 10.1021/acsmedchemlett.7b00118 BindingDB Entry DOI: 10.7270/Q2MK6GBM
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458229 (CHEMBL4214411) Show SMILES COc1ccc2C\C(=C/c3ccc(OCCCN4CCCCC4)cc3)C(=O)c2c1 Show InChI InChI=1S/C25H29NO3/c1-28-23-11-8-20-17-21(25(27)24(20)18-23)16-19-6-9-22(10-7-19)29-15-5-14-26-12-3-2-4-13-26/h6-11,16,18H,2-5,12-15,17H2,1H3/b21-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University Duesseldorf Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method				Eur J Med Chem 148: 487-497 (2018) Article DOI: 10.1016/j.ejmech.2018.02.015 BindingDB Entry DOI: 10.7270/Q2Z89G1Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50458224 (CHEMBL2297871) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H25NO2/c20-18(15-5-6-15)16-7-9-17(10-8-16)21-14-4-13-19-11-2-1-3-12-19/h7-10,15H,1-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor stably expressed in HEK293 cell membrane after 90 mins				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111785 BindingDB Entry DOI: 10.7270/Q2Q81HF9
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50580515 (CHEMBL5088622) Show SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCC4)cc-23)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50580520 (CHEMBL5082920) Show SMILES Nc1nc2-c3cc(OCCCN4CCCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from mouse brain cortex H3 receptor after 60 mins by gamma counting method				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50520936 (CHEMBL4593213) Show SMILES CCC(=O)c1ccc(OCCCCN2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C22H29N3O2/c1-2-22(26)19-5-7-21(8-6-19)27-18-4-3-13-24-14-16-25(17-15-24)20-9-11-23-12-10-20/h5-12H,2-4,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from full length recombinant human H3R expressed in HEK293 cell membranes after 90 mins by beta scintilla...				Bioorg Med Chem 26: 6056-6066 (2018) Article DOI: 10.1016/j.bmc.2018.11.010 BindingDB Entry DOI: 10.7270/Q2NV9NNX
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50405713 (CHEMBL4173854) Show SMILES CC(C)(C)c1ccc(OCCCN2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C15H18ClNO3S2/c1-9(8-21)14(18)17-7-12(6-13(17)15(19)20)22-11-4-2-10(16)3-5-11/h2-5,9,12-13,21H,6-8H2,1H3,(H,19,20)/t9-,12+,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from recombinant human H3 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countin...				Eur J Med Chem 152: 223-234 (2018) Article DOI: 10.1016/j.ejmech.2018.04.043 BindingDB Entry DOI: 10.7270/Q2697632
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from rat brain cortex H3 receptor after 60 mins by gamma counting method				Bioorg Med Chem 26: 2573-2585 (2018) Article DOI: 10.1016/j.bmc.2018.04.023 BindingDB Entry DOI: 10.7270/Q2TQ641P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50580520 (CHEMBL5082920) Show SMILES Nc1nc2-c3cc(OCCCN4CCCC4)ccc3C(=O)c2c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00914 BindingDB Entry DOI: 10.7270/Q22F7S8G
					More data for this Ligand-Target Pair

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