| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50247053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1712142 (CHEMBL4122191) |
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| Ki | 14±n/a nM |
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| Citation |  ?a?ewska, D; Kaleta, M; Hagenow, S; Mogilski, S; Latacz, G; Karcz, T; Lubelska, A; Honkisz, E; Handzlik, J; Reiner, D; Sata?a, G; Filipek, B; Stark, H; Kie?-Kononowicz, K Novel naphthyloxy derivatives - Potent histamine H Bioorg Med Chem26:2573-2585 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_MOUSE | Hrh3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48560.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_988451 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50247053 |
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| n/a |
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| Name | BDBM50247053 |
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| Synonyms: | 1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine | CHEMBL462605 | Tiprolisant |
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| Type | Small organic molecule |
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| Emp. Form. | C17H26ClNO |
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| Mol. Mass. | 295.847 |
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| SMILES | Clc1ccc(CCCOCCCN2CCCCC2)cc1 |
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| Structure | 
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