Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50327493'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327493 (8-(1-isopropylpiperidin-4-yloxy)-2-(2-methoxyethyl...) Show SMILES COCCN1CCn2c(cc3cc(OC4CCN(CC4)C(C)C)ccc23)C1=O Show InChI InChI=1S/C22H31N3O3/c1-16(2)23-8-6-18(7-9-23)28-19-4-5-20-17(14-19)15-21-22(26)24(12-13-27-3)10-11-25(20)21/h4-5,14-16,18H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-RAMH from human histamine H3 receptor				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327493 (8-(1-isopropylpiperidin-4-yloxy)-2-(2-methoxyethyl...) Show SMILES COCCN1CCn2c(cc3cc(OC4CCN(CC4)C(C)C)ccc23)C1=O Show InChI InChI=1S/C22H31N3O3/c1-16(2)23-8-6-18(7-9-23)28-19-4-5-20-17(14-19)15-21-22(26)24(12-13-27-3)10-11-25(20)21/h4-5,14-16,18H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant histamine H3 receptor assessed as effect on [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair