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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50383444'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50383444
PNG
(CHEMBL2031604)
Show SMILES C1CCN(CC1)C1CCN(CC1)c1nnc(s1)-c1cccc2ccnn12
Show InChI InChI=1S/C19H24N6S/c1-2-11-23(12-3-1)15-8-13-24(14-9-15)19-22-21-18(26-19)17-6-4-5-16-7-10-20-25(16)17/h4-7,10,15H,1-3,8-9,11-14H2
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PC cid
PC sid
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Article
PubMed
 3.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...

Bioorg Med Chem Lett 22: 3354-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.076
BindingDB Entry DOI: 10.7270/Q2DN462S
More data for this
Ligand-Target Pair