BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM85830'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM85830 (VUF5202) Show SMILES Clc1ccc(CNCCCCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by PDSP K_i Database									J Pharmacol Exp Ther 299: 908-14 (2001) BindingDB Entry DOI: 10.7270/Q2JS9P1N
Vrije Universiteit Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM85830 (VUF5202) Show SMILES Clc1ccc(CNCCCCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Activity against human H3 receptor as measured by CRE-mediated beta galactosidase reporter gene assay in forskolin-stimulated SK-N-MC cells				J Med Chem 49: 2549-57 (2006) Article DOI: 10.1021/jm0504353 BindingDB Entry DOI: 10.7270/Q2S46T8X
Vrije Universiteit Amsterdam Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM85830 (VUF5202) Show SMILES Clc1ccc(CNCCCCCc2cnc[nH]2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a
De Novo Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortex				J Med Chem 44: 1666-74 (2001) BindingDB Entry DOI: 10.7270/Q2WH2QP8
De Novo Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair