BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110292'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)		BDBM50110292
PNG
(CHEMBL14781 | Methyl-(2-piperidin-1-yl-ethyl)-(1,2...)
Show SMILES CN(CCN1CCCCC1)c1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C21H29N3/c1-23(15-16-24-13-7-2-8-14-24)21-17-9-3-5-11-19(17)22-20-12-6-4-10-18(20)21/h3,5,9,11H,2,4,6-8,10,12-16H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine

J Med Chem 45: 1128-41 (2002)


BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair