Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110304 ((7-Chloro-quinolin-4-yl)-(5-piperidin-1-yl-pentyl)...) Show SMILES Clc1ccc2c(NCCCCCN3CCCCC3)ccnc2c1 Show InChI InChI=1S/C19H26ClN3/c20-16-7-8-17-18(9-11-22-19(17)15-16)21-10-3-1-4-12-23-13-5-2-6-14-23/h7-9,11,15H,1-6,10,12-14H2,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair