Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10' and Ligand = 'BDBM50221740'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Mus musculus-Mus musculus (Mouse))	BDBM50221740 (CHEMBL1790598) Show SMILES [H][C@@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CCCCCCN(O)C=O)NC2=O)[C@H](C)CC Show InChI InChI=1S/C31H47N5O7/c1-4-21(2)27-31(41)36-18-10-8-12-26(36)30(40)32-24(11-7-5-6-9-17-35(42)20-37)28(38)33-25(29(39)34-27)19-22-13-15-23(43-3)16-14-22/h13-16,20-21,24-27,42H,4-12,17-19H2,1-3H3,(H,32,40)(H,33,38)(H,34,39)/t21-,24+,25-,26+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology Curated by ChEMBL					Assay Description Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cells				Bioorg Med Chem Lett 14: 2427-31 (2004) Article DOI: 10.1016/j.bmcl.2004.03.018 BindingDB Entry DOI: 10.7270/Q20V8DC5
					More data for this Ligand-Target Pair