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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50263460'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50263460
PNG
(CHEMBL4084164)
Show SMILES ONC(=O)\C=C\c1ccc(Cn2c3C4CCCC(=O)N4CCc3c3ccccc23)cc1
Show InChI InChI=1S/C25H25N3O3/c29-23(26-31)13-12-17-8-10-18(11-9-17)16-28-21-5-2-1-4-19(21)20-14-15-27-22(25(20)28)6-3-7-24(27)30/h1-2,4-5,8-13,22,31H,3,6-7,14-16H2,(H,26,29)/b13-12+
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PC cid
PC sid
UniChem
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Institute of Pharmacy, Faculty of Chemistry and Pharmacy , University of Regensburg , 93040 Regensburg , Germany.

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...

J Med Chem 61: 3454-3477 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01593
BindingDB Entry DOI: 10.7270/Q24B33S0
More data for this
Ligand-Target Pair