Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50507696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50507696 (CHEMBL4462263) Show SMILES ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3ccc(O)cc3)c2=O)cc1 Show InChI InChI=1S/C24H21N3O5/c28-19-11-7-16(8-12-19)13-14-26-23(30)20-3-1-2-4-21(20)27(24(26)31)15-17-5-9-18(10-6-17)22(29)25-32/h1-12,28,32H,13-15H2,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	845	n/a	n/a	n/a	n/a	n/a	n/a
AnnJi Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human full-length recombinant HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKAcKAc as substrate ...				J Med Chem 62: 857-874 (2019) Article DOI: 10.1021/acs.jmedchem.8b01590 BindingDB Entry DOI: 10.7270/Q2833WBH
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