Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase SMYD3' and Ligand = 'BDBM432827'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM432827 (5-cyclopropyl-N-((2S,4S)-2-methyl-1- (((1-phenethy...) Show SMILES C[C@H]1C[C@H](CCN1S(=O)(=O)CC1CCN(CCc2ccccc2)CC1)NC(=O)c1cc(on1)C1CC1 |r| Show InChI InChI=1S/C27H38N4O4S/c1-20-17-24(28-27(32)25-18-26(35-29-25)23-7-8-23)12-16-31(20)36(33,34)19-22-10-14-30(15-11-22)13-9-21-5-3-2-4-6-21/h2-6,18,20,22-24H,7-17,19H2,1H3,(H,28,32)/t20-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
EPIZYME, INC. US Patent					Assay Description The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....				US Patent US10577363 (2020) BindingDB Entry DOI: 10.7270/Q2BZ68G7
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