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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM50147264'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))
BDBM50147264
PNG
(4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Show SMILES Cc1c(C2CCCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24N2O3/c1-12-14(13-8-4-2-5-9-13)15(19)21-18(12)16(20)17-10-6-3-7-11-17/h13H,2-11H2,1H3
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone-sensitive lipase


(Rattus norvegicus (Rat))
BDBM50147264
PNG
(4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Show SMILES Cc1c(C2CCCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24N2O3/c1-12-14(13-8-4-2-5-9-13)15(19)21-18(12)16(20)17-10-6-3-7-11-17/h13H,2-11H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


J Med Chem 51: 6478-94 (2008)


Article DOI: 10.1021/jm800718k
BindingDB Entry DOI: 10.7270/Q23778KJ
More data for this
Ligand-Target Pair
Hormone-sensitive lipase


(Homo sapiens (Human))
BDBM50147264
PNG
(4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Show SMILES Cc1c(C2CCCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24N2O3/c1-12-14(13-8-4-2-5-9-13)15(19)21-18(12)16(20)17-10-6-3-7-11-17/h13H,2-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair