Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50179013'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179013 (CHEMBL205924 | moracin O) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C19H18O5/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Korean Research Institute of Biosciences and Biotechnology Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysis				J Nat Prod 72: 39-43 (2009) Article DOI: 10.1021/np800491u BindingDB Entry DOI: 10.7270/Q27947GK
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179013 (CHEMBL205924 | moracin O) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C19H18O5/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.76	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair