Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin receptor (Homo sapiens (Human)) | BDBM50339062 (4-(3-(4-amino-5-(8-fluoro-2-phenylquinolin-7-yl)im...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of auto-phosphorylation of human IR expressed in human HepG2 cells after 2 hrs by luminometry | ACS Med Chem Lett 1: 510-515 (2010) Article DOI: 10.1021/ml100178g BindingDB Entry DOI: 10.7270/Q2J966NZ | |||||||||||
More data for this Ligand-Target Pair |